Molecule type: protein
Alternative name(s): MAPKAPK1A RSK1
External ID: Q15418


Modifications

Variants

Modification: (TPO)734

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 725-735

This selection has only 1 possible fragment in the database.


Showing 1 to 25 of 142 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.

pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
SFN P31947 1-248 100_uM_FCA 5.86 N/D 0.99 2.51 4 / 4
YWHAZ P63104 1-245 5.81 N/D 0.99 2.42 5 / 5
SFN P31947 1-248 5.26 0.26 0.98 4.03 6 / 6
YWHAE P62258 1-255 5.26 0.26 0.98 3.21 6 / 6
YWHAQ P27348 1-245 5.00 N/D 0 0 1 / 1
YWHAB P31946 1-246 5.00 0.00 0 0 2 / 2
YWHAG P61981 1-247 100_uM_FCA 5.00 N/D 0 0 1 / 1
YWHAG P61981 1-247 5.00 0.00 0 0 2 / 2
YWHAH Q04917 1-246 5.00 N/D 0 0 1 / 1
MAST2 Q6P0Q8 1102-1193 4.99 0.17 0.76 0 5 / 5
PDZD7 Q9H5P4 858-953 4.90 0.01 0.54 0 4 / 4
ARHGEF12 Q9NZN5 67-151 4.87 0.00 0.48 0 4 / 4
MAST1 Q9Y2H9 965-1056 4.74 0.24 0.19 0 4 / 4
SCRIB Q14160 999-1093 4.71 0.10 0.4 0 4 / 4
LNX1 Q8TBB1 261-371 4.63 N/D 0.49 0 1 / 1
SYNJ2BP P57105 6-103 4.63 0.15 0.34 0 5 / 5
HTRA1 Q92743 365-480 4.60 0.09 0.41 0 5 / 5
PTPN3 P26045 505-597 4.48 N/D 0.42 0 1 / 1
GOPC Q9HD26 278-373 4.44 0.22 0.34 0 4 / 4
MAGI2 Q86UL8 410-522 4.35 0.43 0.14 0 5 / 5
MAGI2 Q86UL8 772-865 4.32 N/D 0.28 0 1 / 1
PDZRN4 Q6ZMN7 214-318 4.31 0.01 0.27 0 4 / 4
ARHGEF11 O15085 41-126 4.29 N/D 0.24 0 1 / 1
MAGI1 Q96QZ7 456-580 4.23 0.09 0.28 0 4 / 4
NHERF4 Q86UT5 106-208 4.23 N/D 0.29 0 1 / 1
Showing 1 to 25 of 142 results
Showing 1 to 25 of 142 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.



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