1433S

Molecule type: protein
Alternative name(s): SFN HME1
External ID: P31947


Modifications

Variants

This selection has 2 unique variants

non-modified profile
100_uM_FCA modified profile
Fragments

Fragments

Fragment: 1-248

This selection has only 1 possible fragment in the database.


Showing 1 to 25 of 742 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.
pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
RPS6KA1 Q15418 725-735 (TPO)733 RKLPSTTL-- 5.80 0.17 0.99 7.26 13 / 13
YAP1 P46937 271-280 (SEP)276 QRISQSAPVK 5.67 0.14 0.99 15.94 16 / 16
MPRIP Q6WCQ1 988-997 (SEP)993 IMKSKSNPDF 5.54 0.02 0.98 18.34 13 / 13
IRS2 Q9Y4H2 574-583 (TPO)579 RTYSLTTPAR 5.53 0.27 0.98 24.74 16 / 16
LCP2 Q13094 371-382 (SEP)376 FPQSASLPPY 5.52 0.71 0.97 4.86 10 / 10
RPS6KA1 Q15418 725-735 (TPO)734 KLPSTTL--- 5.46 0.35 0.98 5.02 10 / 10
PPP1R3D O95685 69-78 (SEP)74 LRRARSLPSS 5.31 0.05 0.96 17.21 13 / 13
FAM122B Q7Z309 20-29 (SEP)25 LRRSSSAPLI 5.29 0.23 0.98 15.15 10 / 10
MAP3K3 Q99759 161-170 (SEP)166 RSRHLSVSSQ 5.28 N/D 0.96 3.74 4 / 4
AKAP13 Q12802 2462-2471 (TPO)2467 PRRAETFGGF 5.25 0.07 0.95 22.17 13 / 13
FAM53B Q14153 164-173 (SEP)169 RSSSFSLPSR 5.13 0.19 0.95 21.26 16 / 16
OSBPL3 Q9H4L5 315-324 (SEP)320 EEKNYSDGSE 5.06 N/D 0.93 1.41 4 / 4
TIAM1 Q13009 1432-1441 (SEP)1437 MSRAVSAPSK 5.04 0.14 0.93 9.47 13 / 13
MARK2 Q7KZI7 35-44 (SEP)40 IRGRNSATSA 5.03 N/D 0.92 2.39 4 / 4
PAK4 O96013 202-211 (TPO)207 GRPFNTYPRA 5.03 0.04 0.93 2.55 6 / 6
PI4KB Q9UBF8 289-298 (SEP)294 LKRTASNPKV 5.00 0.00 0 0 2 / 2
PHACTR4 Q8IZ21 459-468 (SEP)464 LGRTRSLPIT 4.99 0.05 0.92 20.64 13 / 13
CDC25B P30305 146-155 (SEP)151 IRRFQSMPVR 4.94 0.38 0.89 9.85 13 / 13
OSBPL6 Q9BZF3 285-294 (SEP)290 LQRTQSAPNF 4.92 0.77 0.74 8.9 10 / 10
HDAC7 Q8WUI4 481-490 (SEP)486 LSRAQSSPAA 4.92 0.04 0.91 16.83 13 / 13
HDAC4 P56524 627-636 (SEP)632 LSRAQSSPAS 4.91 0.12 0.91 6.74 13 / 13
KIF1C O43896 1077-1086 (TPO)1082 RYPPYTTPPR 4.90 0.15 0.92 9.99 16 / 16
SYDE2 Q5VT97 1188-1197 (SEP)1193 NKLNMSF--- 4.89 0.15 0.9 13.43 13 / 13
FAM117B Q6P1L5 451-460 (TPO)456 LPKYATSPKP 4.89 0.12 0.9 15.54 13 / 13
PLEKHA7 Q6IQ23 421-430 (SEP)426 NPEKHSQRKS 4.89 N/D 0.31 0.76 5 / 13
Showing 1 to 25 of 742 results
Showing 1 to 25 of 742 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.


This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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