YWHAG

Molecule type: protein
Alternative name(s): YWHAG
External ID: P61981


Modifications

Variants

This selection has 2 unique variants

non-modified profile
100_uM_FCA modified profile
Fragments

Fragments

Fragment: 1-247

This selection has only 1 possible fragment in the database.


Showing 1 to 25 of 773 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.
pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
YAP1 P46937 271-280 (SEP)276 QRISQSAPVK 6.18 0.13 0.99 10.7 13 / 13
MPRIP Q6WCQ1 988-997 (SEP)993 IMKSKSNPDF 5.81 0.60 1 3.92 6 / 6
FAM53B Q14153 164-173 (SEP)169 RSSSFSLPSR 5.70 0.30 0.99 13.3 16 / 16
DOCK11 Q5JSL3 1347-1356 (TPO)1352 DRKSQTMPAL 5.68 0.33 0.97 5.41 5 / 5
IRS2 Q9Y4H2 574-583 (TPO)579 RTYSLTTPAR 5.64 0.40 0.99 5.54 12 / 12
PPP1R3D O95685 69-78 (SEP)74 LRRARSLPSS 5.62 0.44 0.99 12.83 10 / 10
HDAC7 Q8WUI4 481-490 (SEP)486 LSRAQSSPAA 5.59 0.06 0.98 17.48 13 / 13
PHACTR4 Q8IZ21 459-468 (SEP)464 LGRTRSLPIT 5.57 0.06 0.98 21.39 13 / 13
AKAP13 Q12802 2462-2471 (TPO)2467 PRRAETFGGF 5.51 0.14 0.98 16.72 13 / 13
FAM122B Q7Z309 20-29 (SEP)25 LRRSSSAPLI 5.49 0.40 0.98 8.3 10 / 10
KIF1B O60333 1136-1145 (SEP)1141 MRRQFSAPNL 5.42 0.08 0.97 13.76 13 / 13
TIAM1 Q13009 1432-1441 (SEP)1437 MSRAVSAPSK 5.37 0.13 0.96 9.9 13 / 13
KIF1C O43896 1077-1086 (TPO)1082 RYPPYTTPPR 5.36 0.37 0 0 9 / 9
HDAC4 P56524 627-636 (SEP)632 LSRAQSSPAS 5.35 0.15 0.96 7.29 13 / 13
HDAC7 Q8WUI4 150-159 (SEP)155 LRKTVSEPNL 5.34 0.15 0.96 25.05 13 / 13
LCP2 Q13094 371-382 (SEP)376 FPQSASLPPY 5.33 0.47 0 0 3 / 3
PLEKHA7 Q6IQ23 560-569 (SEP)565 VPRSISVPPS 5.29 0.44 0.95 13.83 13 / 13
MAP3K3 Q99759 161-170 (SEP)166 RSRHLSVSSQ 5.27 N/D 0.96 3.8 4 / 4
USP8 P40818 712-724 (SEP)718 LKRSYSSPDI 5.27 0.38 0.99 8.65 7 / 7
FOXO3 O43524 408-417 (SEP)413 MQRSSSFPYT 5.26 0.16 0.96 14.36 13 / 13
KIAA0930 Q6ICG6 284-293 (SEP)289 RVTSFSTPPT 5.24 0.08 0.96 27.02 19 / 19
BRAF P15056 724-733 (SEP)729 IHRSASEPSL 5.24 0.59 0.92 4.57 13 / 13
GAB2 Q9UQC2 386-395 (TPO)391 IPRRNTLPAM 5.20 0.29 0.98 7.25 7 / 7
CDC25B P30305 225-234 (SEP)230 AQRPSSAPDL 5.18 0.12 0.95 21.65 13 / 13
FAM117B Q6P1L5 451-460 (TPO)456 LPKYATSPKP 5.12 0.12 0.94 6.64 10 / 10
Showing 1 to 25 of 773 results
Showing 1 to 25 of 773 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.


This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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