YWHAH

Molecule type: protein
Alternative name(s): YWHAH YWHA1
External ID: Q04917


Modifications

Variants

Modification: none

This selection has only 1 modification in the database.

Fragments

Fragments

Fragment: 1-246

This selection has only 1 possible fragment in the database.


Showing 1 to 25 of 680 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.
pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
MPRIP Q6WCQ1 988-997 (SEP)993 IMKSKSNPDF 6.15 N/D 0.99 7 5 / 5
YAP1 P46937 72-81 (TPO)77 VMNPKTANVP 6.00 N/D 0 0 1 / 1
IRS2 Q9Y4H2 574-583 (TPO)579 RTYSLTTPAR 5.92 0.08 0 0 4 / 4
YAP1 P46937 271-280 (SEP)276 QRISQSAPVK 5.78 0.24 0.99 11.01 8 / 8
FAM122B Q7Z309 20-29 (SEP)25 LRRSSSAPLI 5.77 N/D 0.99 5.26 5 / 5
PPP1R3D O95685 69-78 (SEP)74 LRRARSLPSS 5.60 N/D 0.98 6.38 5 / 5
PHACTR4 Q8IZ21 459-468 (SEP)464 LGRTRSLPIT 5.52 N/D 0.98 6.97 5 / 5
DOCK11 Q5JSL3 1347-1356 (TPO)1352 DRKSQTMPAL 5.46 N/D 0.97 6.52 5 / 5
FAM53B Q14153 164-173 (SEP)169 RSSSFSLPSR 5.42 0.05 0.97 7.74 8 / 8
USP8 P40818 712-724 (SEP)718 LKRSYSSPDI 5.42 N/D 0.97 9.55 5 / 5
HDAC7 Q8WUI4 481-490 (SEP)486 LSRAQSSPAA 5.36 N/D 0.97 10.48 5 / 5
BRAF P15056 724-733 (SEP)729 IHRSASEPSL 5.31 N/D 0.96 7.5 5 / 5
AKAP13 Q12802 2462-2471 (TPO)2467 PRRAETFGGF 5.25 N/D 0.96 7.3 5 / 5
DENND4A Q7Z401 1276-1285 (SEP)1281 RDRLWSSPAF 5.22 N/D 0.96 3.91 5 / 5
GAB2 Q9UQC2 386-395 (TPO)391 IPRRNTLPAM 5.19 N/D 0.95 8.13 5 / 5
TIAM1 Q13009 1432-1441 (SEP)1437 MSRAVSAPSK 5.18 N/D 0.95 8.78 5 / 5
KIF1C O43896 1077-1086 (TPO)1082 RYPPYTTPPR 5.12 0.12 0 0 4 / 4
FAM117B Q6P1L5 451-460 (TPO)456 LPKYATSPKP 5.11 N/D 0.94 4.22 5 / 5
HDAC4 P56524 627-636 (SEP)632 LSRAQSSPAS 5.11 N/D 0.94 4.45 5 / 5
KIF1B O60333 1136-1145 (SEP)1141 MRRQFSAPNL 5.07 N/D 0.94 6.11 5 / 5
ARHGEF16 Q5VV41 487-496 (SEP)492 FSKVKSLPLI 5.05 N/D 0.94 5.15 5 / 5
SYDE2 Q5VT97 1188-1197 (SEP)1193 NKLNMSF--- 5.04 N/D 0.93 6.6 5 / 5
CDC25B P30305 146-155 (SEP)151 IRRFQSMPVR 5.01 N/D 0.93 7.84 5 / 5
HDAC7 Q8WUI4 150-159 (SEP)155 LRKTVSEPNL 5.01 N/D 0.93 8.2 5 / 5
BRAF P15056 360-369 (SEP)365 RDRSSSAPNV 5.00 N/D 0 0 1 / 1
Showing 1 to 25 of 680 results
Showing 1 to 25 of 680 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.


This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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