BRAF

Molecule type: protein
Alternative name(s): BRAF BRAF1 RAFB1
External ID: P15056


Modifications

Variants

Modification: (SEP)365

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 360-369

This selection has only 1 possible fragment in the database.


Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.
pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
YWHAB P31946 1-246 — — 5.00 N/D 0 0 1 / 1
YWHAG P61981 1-247 — — 5.00 0.00 0 0 2 / 2
YWHAZ P63104 1-245 — — 5.00 N/D 0 0 1 / 1
YWHAH Q04917 1-246 — — 5.00 N/D 0 0 1 / 1
YWHAQ P27348 1-245 — — 4.96 N/D 0.92 1.69 5 / 5
SFN P31947 1-248 — — 4.59 0.11 0.83 4.02 9 / 9
YWHAE P62258 1-255 — — 4.42 0.08 0.77 2.91 9 / 9
SFN P31947 1-248 100_uM_FCA — not detectable N/D -0.1 0.11 0 / 4
Showing 1 to 8 of 8 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.


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