BRAF

Molecule type: protein
Alternative name(s): BRAF BRAF1 RAFB1
External ID: P15056


Modifications

Variants

Modification: (SEP)729

This selection has only 1 modification in the database.

Fragments

Fragments

Fragment: 724-733

A specific fragment is selected.

See all possible fragments


Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.
pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
YWHAG P61981 1-247 100_uM_FCA — 5.91 N/D 0.99 4.99 4 / 4
YWHAH Q04917 1-246 — — 5.31 N/D 0.96 7.5 5 / 5
YWHAZ P63104 1-245 — — 5.17 N/D 0.95 6.06 5 / 5
YWHAG P61981 1-247 — — 4.90 0.43 0.88 3.05 9 / 9
YWHAQ P27348 1-245 — — 4.86 N/D 0.9 8.24 5 / 5
YWHAB P31946 1-246 — — 4.78 0.26 0.87 3.1 9 / 9
YWHAE P62258 1-255 — — 4.36 0.07 0.74 2.65 9 / 9
SFN P31947 1-248 — — 4.28 N/D 0.73 7.39 5 / 5
SFN P31947 1-248 100_uM_FCA — 4.15 N/D 0.61 5.83 4 / 4
Showing 1 to 9 of 9 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.


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