Molecule type: protein
Alternative name(s): YWHAG
External ID: P61981


Modifications

Variants

Modification: none

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 1-247

This selection has only 1 possible fragment in the database.


Showing 1 to 25 of 755 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.

pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
MPRIP Q6WCQ1 988-997 (SEP)993 IMKSKSNPDF 6.22 0.21 1 3.92 5 / 5
YAP1 P46937 271-280 (SEP)276 QRISQSAPVK 6.17 0.15 0.99 7.9 9 / 9
FAM122B Q7Z309 20-29 (SEP)25 LRRSSSAPLI 5.74 0.25 0.98 8.3 9 / 9
DOCK11 Q5JSL3 1347-1356 (TPO)1352 DRKSQTMPAL 5.68 0.33 0.97 5.41 5 / 5
HDAC7 Q8WUI4 481-490 (SEP)486 LSRAQSSPAA 5.64 0.01 0.98 14.78 9 / 9
FAM53B Q14153 164-173 (SEP)169 RSSSFSLPSR 5.62 0.29 0.99 13.3 15 / 15
PHACTR4 Q8IZ21 459-468 (SEP)464 LGRTRSLPIT 5.60 0.06 0.98 14.26 9 / 9
IRS2 Q9Y4H2 574-583 (TPO)579 RTYSLTTPAR 5.56 0.40 0 0 8 / 8
AKAP13 Q12802 2462-2471 (TPO)2467 PRRAETFGGF 5.55 0.16 0.98 11.58 9 / 9
PPP1R3D O95685 69-78 (SEP)74 LRRARSLPSS 5.46 0.46 0.99 6.42 6 / 6
TIAM1 Q13009 1432-1441 (SEP)1437 MSRAVSAPSK 5.46 0.03 0.98 10.94 9 / 9
KIF1C O43896 1077-1086 (TPO)1082 RYPPYTTPPR 5.44 0.36 0 0 8 / 8
HDAC4 P56524 627-636 (SEP)632 LSRAQSSPAS 5.44 0.12 0.98 7.19 9 / 9
USP8 P40818 712-724 (SEP)718 LKRSYSSPDI 5.40 0.40 0.99 8.65 6 / 6
KIF1B O60333 1136-1145 (SEP)1141 MRRQFSAPNL 5.37 0.05 0.96 9.17 9 / 9
FOXO3 O43524 408-417 (SEP)413 MQRSSSFPYT 5.32 0.17 0.96 9.57 9 / 9
DENND4A Q7Z401 1276-1285 (SEP)1281 RDRLWSSPAF 5.32 N/D 0.96 3.97 5 / 5
GAB2 Q9UQC2 386-395 (TPO)391 IPRRNTLPAM 5.30 0.31 0.98 7.25 6 / 6
HDAC7 Q8WUI4 150-159 (SEP)155 LRKTVSEPNL 5.28 0.15 0.96 16.7 9 / 9
CDC25B P30305 225-234 (SEP)230 AQRPSSAPDL 5.27 0.00 0.96 14.43 9 / 9
MAP3K3 Q99759 161-170 (SEP)166 RSRHLSVSSQ 5.27 N/D 0.96 3.8 4 / 4
KIAA0930 Q6ICG6 284-293 (SEP)289 RVTSFSTPPT 5.20 0.02 0.96 19.65 15 / 15
ABLIM1 O14639 701-710 (SEP)706 MDRGVSMPNM 5.20 0.05 0.96 5.65 9 / 9
RALGPS2 Q86X27 417-426 (SEP)422 NRLYHSLGPV 5.17 N/D 0.65 0.56 5 / 9
CDK17 Q00537 70-79 (SEP)75 LRRPHSVIGG 5.16 0.05 0.96 11.18 9 / 9
Showing 1 to 25 of 755 results
Showing 1 to 25 of 755 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.



This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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