Molecule type: protein
Alternative name(s): YWHAQ
External ID: P27348


Modifications

Variants

Modification: none

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 1-245

A specific fragment is selected.

See all possible fragments


Showing 1 to 25 of 675 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.

pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
MPRIP Q6WCQ1 988-997 (SEP)993 IMKSKSNPDF 6.01 N/D 0.99 10.24 5 / 5
RPS6KA1 Q15418 725-735 (TPO)733 RKLPSTTL-- 5.82 N/D 0.99 5.29 5 / 5
YAP1 P46937 271-280 (SEP)276 QRISQSAPVK 5.82 0.07 0.99 11.16 8 / 8
FAM122B Q7Z309 20-29 (SEP)25 LRRSSSAPLI 5.79 N/D 0.99 7.86 5 / 5
IRS2 Q9Y4H2 574-583 (TPO)579 RTYSLTTPAR 5.68 0.33 0 0 4 / 4
LCP2 Q13094 371-382 (SEP)376 FPQSASLPPY 5.62 N/D 0.98 1.79 5 / 5
PPP1R3D O95685 69-78 (SEP)74 LRRARSLPSS 5.41 N/D 0.97 6.65 5 / 5
AKAP13 Q12802 2462-2471 (TPO)2467 PRRAETFGGF 5.35 N/D 0.97 7.68 5 / 5
PHACTR4 Q8IZ21 459-468 (SEP)464 LGRTRSLPIT 5.34 N/D 0.97 7.19 5 / 5
DOCK11 Q5JSL3 1347-1356 (TPO)1352 DRKSQTMPAL 5.27 N/D 0.96 6.84 5 / 5
HDAC7 Q8WUI4 481-490 (SEP)486 LSRAQSSPAA 5.26 N/D 0.96 10.89 5 / 5
USP8 P40818 712-724 (SEP)718 LKRSYSSPDI 5.17 N/D 0.95 10.11 5 / 5
KIF1C O43896 1077-1086 (TPO)1082 RYPPYTTPPR 5.12 0.29 0.97 5.19 8 / 8
FAM53B Q14153 164-173 (SEP)169 RSSSFSLPSR 5.08 0.12 0.95 7.92 8 / 8
TIAM1 Q13009 1432-1441 (SEP)1437 MSRAVSAPSK 5.05 N/D 0.94 9.22 5 / 5
GAB2 Q9UQC2 386-395 (TPO)391 IPRRNTLPAM 5.01 N/D 0.93 8.43 5 / 5
HDAC4 P56524 627-636 (SEP)632 LSRAQSSPAS 5.01 N/D 0.93 4.74 5 / 5
PAK4 O96013 202-211 (TPO)207 GRPFNTYPRA 5.00 N/D 0 0 1 / 1
PLEKHA7 Q6IQ23 533-542 (TPO)538 RHGSPTAPI- 5.00 N/D 0 0 1 / 1
RPS6KA1 Q15418 725-735 (TPO)734 KLPSTTL--- 5.00 N/D 0 0 1 / 1
TBC1D4 O60343 699-708 (SEP)704 LHTSFSAPSF 5.00 N/D 0 0 1 / 1
BRAF P15056 360-369 (SEP)365 RDRSSSAPNV 4.96 N/D 0.92 1.99 5 / 5
HDAC7 Q8WUI4 150-159 (SEP)155 LRKTVSEPNL 4.95 N/D 0.92 8.4 5 / 5
RALGPS2 Q86X27 356-365 (TPO)361 EFKSATFPNA 4.95 N/D 0.92 9.09 5 / 5
SYDE2 Q5VT97 1188-1197 (SEP)1193 NKLNMSF--- 4.95 N/D 0.92 6.83 5 / 5
Showing 1 to 25 of 675 results
Showing 1 to 25 of 675 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.



This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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