CASK

Molecule type: protein
Alternative name(s): LIN2
External ID: O14936


Modifications

Variants

Modification: none

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 487-570

A specific fragment is selected.

See all possible fragments

No statistical (volcano) data available for this fragment.

Showing fragment-specific summary data without graphics instead. (Will be fixed soon.)

Showing 1 to 25 of 452 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.
pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
PRKN O60260 456-465 — VCMGDHWFDV 4.83 N/D 0.52 0 1 / 1
HPV51-E6 P26554 142-151 — RTRQRNETQV 4.55 N/D 0.08 0 1 / 2
MAP2K2 P36507 391-400 — QPGTPTRTAV 4.38 N/D 0.02 0 1 / 2
CNTNAP4 Q9C0A0 1299-1308 — VNENQKEYFF 3.79 N/D 0.1 0 1 / 1
NECTIN3 Q9NQS3 540-549 — SVISRREWYV 3.75 N/D 0.09 0 1 / 1
TRAF7 Q6Q0C0 661-670 — VDSTVKVWTC 3.75 N/D 0.09 0 1 / 1
PKP4 Q99569 1183-1192 — QYPGSPDSWV 3.74 N/D 0.09 0 1 / 1
FAM71C Q8NEG0 232-241 — STYCDYTIEI 3.67 N/D 0.08 0 1 / 1
OR10G3 Q8NGC4 304-313 — LRSPRTPSEV 3.61 N/D 0.07 0 1 / 1
FZD10 Q9ULW2 572-581 — EIPAQSPTCV 3.59 N/D 0.07 0 1 / 1
NRXN3 Q9HDB5 628-637 — QKNKDREYYV 3.55 N/D 0.06 0 1 / 1
NRXN3 Q9Y4C0 1634-1643 rs746444206 QKNKDKEYYV 3.55 N/D 0.06 0 1 / 1
ABRAXAS2 Q15018 406-415 — DPRNTQTSQI 3.55 N/D 0.06 0 1 / 1
MERS-E K9N5R3 73-82 — KPPLPPDEWV 3.55 N/D 0.06 0 1 / 1
PKN2 Q16513 975-984 — RDFDYIADWC 3.54 N/D 0.06 0 1 / 1
TMEM178A Q8NBL3 288-297 — QLKSGRDSTV 3.54 N/D 0.06 0 1 / 1
CACNA1A O00555 2497-2506 — PYSESDDDWC 3.53 N/D 0.06 0 1 / 1
BANF1 O75531 80-89 — CLREWCDAFL 3.52 N/D 0.06 0 1 / 1
MARCHF9 Q86YJ5 337-346 — REVVMRVTTV 3.50 N/D 0.05 0 1 / 1
TRIM29 Q14134 579-588 — KSGKQTMLVV 3.48 N/D 0.05 0 1 / 1
MERS-E K9N5R3 71-82 — KPPLPPDEWV 3.48 N/D 0 0 1 / 3
PTEN P60484 393-403 — EDQHTQITKV 3.47 N/D 0 0 1 / 2
ABCA1 O95477 2252-2261 — QDEKVKESYV not detectable N/D -0 0 0 / 2
ABCA2 Q9BZC7 2426-2435 — QLSFNTDTLC not detectable N/D -0.01 0 0 / 1
ABCA7 Q8IZY2 2137-2146 — DDPSTAETVL not detectable N/D -0.06 0 0 / 1
Showing 1 to 25 of 452 results
Showing 1 to 25 of 452 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.


This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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