Molecule type: protein
Alternative name(s): SFN HME1
External ID: P31947


Modifications

Variants

Modification: 100_uM_FCA

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 1-248

A specific fragment is selected.

See all possible fragments


Showing 1 to 25 of 648 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.

pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
LCP2 Q13094 371-382 (SEP)376 FPQSASLPPY 6.52 N/D 1 5.44 4 / 4
RPS6KA1 Q15418 725-735 (TPO)733 RKLPSTTL-- 5.90 N/D 0.99 2.72 4 / 4
RPS6KA1 Q15418 725-735 (TPO)734 KLPSTTL--- 5.86 N/D 0.99 2.81 4 / 4
YAP1 P46937 271-280 (SEP)276 QRISQSAPVK 5.79 N/D 0.99 5.61 4 / 4
IRS2 Q9Y4H2 574-583 (TPO)579 RTYSLTTPAR 5.64 N/D 0.98 9.15 4 / 4
MPRIP Q6WCQ1 988-997 (SEP)993 IMKSKSNPDF 5.53 N/D 0.97 6.42 4 / 4
CDC25B P30305 146-155 (SEP)151 IRRFQSMPVR 5.44 N/D 0.97 3.58 4 / 4
TBC1D4 O60343 699-708 (SEP)704 LHTSFSAPSF 5.43 N/D 0.97 6.4 4 / 4
PLEKHA7 Q6IQ23 560-569 (SEP)565 VPRSISVPPS 5.42 N/D 0.97 8.39 4 / 4
PPP1R3D O95685 69-78 (SEP)74 LRRARSLPSS 5.35 N/D 0.96 6.84 4 / 4
AKAP13 Q12802 2462-2471 (TPO)2467 PRRAETFGGF 5.26 N/D 0.95 8.76 4 / 4
FAM53B Q14153 164-173 (SEP)169 RSSSFSLPSR 5.25 N/D 0.95 7.39 4 / 4
PAK4 O96013 202-211 (TPO)207 GRPFNTYPRA 5.08 N/D 0.93 2.85 4 / 4
MARK2 Q7KZI7 35-44 (SEP)40 IRGRNSATSA 5.03 N/D 0.92 2.69 4 / 4
FAM122B Q7Z309 20-29 (SEP)25 LRRSSSAPLI 5.00 N/D 0 0 1 / 1
HDAC5 Q9UQL6 493-502 (SEP)498 LSRTQSSPLP 5.00 N/D 0 0 1 / 1
PI4KB Q9UBF8 289-298 (SEP)294 LKRTASNPKV 5.00 N/D 0 0 1 / 1
PLEKHA7 Q6IQ23 533-542 (TPO)538 RHGSPTAPI- 5.00 N/D 0 0 1 / 1
PHACTR4 Q8IZ21 459-468 (SEP)464 LGRTRSLPIT 4.93 N/D 0.9 8.09 4 / 4
KIF1C O43896 1077-1086 (TPO)1082 RYPPYTTPPR 4.89 N/D 0.9 3.63 4 / 4
SYDE2 Q5VT97 1188-1197 (SEP)1193 NKLNMSF--- 4.87 N/D 0.89 5.37 4 / 4
HDAC7 Q8WUI4 481-490 (SEP)486 LSRAQSSPAA 4.86 N/D 0.89 5.91 4 / 4
TIAM1 Q13009 1432-1441 (SEP)1437 MSRAVSAPSK 4.84 N/D 0.89 3.46 4 / 4
FAM117B Q6P1L5 451-460 (TPO)456 LPKYATSPKP 4.83 N/D 0.88 8.43 4 / 4
KIAA0930 Q6ICG6 284-293 (SEP)289 RVTSFSTPPT 4.79 N/D 0.87 9.08 4 / 4
Showing 1 to 25 of 648 results
Showing 1 to 25 of 648 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.



This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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