Molecule type: protein
Alternative name(s): H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B
External ID: P84243


Modifications

Variants

Modification: none

This selection has only 1 modification in the database.

Fragments

Fragments

Fragment: 1-136

This selection has only 1 possible fragment in the database.


Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.

pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
BIN1 O00499 513-593 5.42 N/D 0.22 0.45 3 / 6
DGKZ Q13574 919-928 IQREDQETAV 4.91 N/D 0.45 4.38 3 / 3
DGKI O75912 1056-1065 IGHEDLETAV 4.79 N/D 0.38 3.38 3 / 3
SYNJ1 O43426 1390-1421 not detectable N/D 0.03 0.08 0 / 6
WEE1 P30291 228-247 not detectable N/D 0.28 1.18 0 / 6
WDHD1 O75717 906-924 not detectable N/D 0.25 1.03 0 / 6
DONSON Q9NYP3 71-88 not detectable N/D 0.25 1.06 0 / 6
BORA Q6PGQ7 18-38 not detectable N/D 0.08 0.24 0 / 6
AMPH P49418 615-695 not detectable N/D 0.36 0.46 0 / 3
ABL1 P00519 56-121 not detectable N/D -0.47 0.46 0 / 3
PRMT2 P55345 24-96 not detectable N/D -0.4 0.37 0 / 3
ARHGEF7 Q14155 178-251 not detectable N/D 0.74 1.5 0 / 3
OBSCN Q5VST9 5594-5674 not detectable N/D 0.22 0.16 0 / 3
SNX27 Q96L92 1-541 not detectable N/D 0.38 0.83 0 / 6
SNX27 Q96L92 40-141 not detectable N/D -0.11 0.02 0 / 12
DGKD Q16760 1205-1214 LSRSAPAVEA not detectable N/D 0.29 1.6 0 / 3
DGKH Q86XP1 1211-1220 LGRSTPQSEV not detectable N/D -0.37 2.43 0 / 3
DGKK Q5KSL6 1262-1271 DPLTPSRSQL not detectable N/D 0.28 2.39 0 / 3
Showing 1 to 18 of 18 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.



This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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