ERBB2

Molecule type: protein
Alternative name(s): HER2 MLN19 NEU NGL
External ID: P04626


Modifications

Variants

Modification: none

This selection has only 1 modification in the database.

Fragments

Fragments

Fragment: 1246-1255

A specific fragment is selected.

See all possible fragments

No statistical (volcano) data available for this fragment.

Showing fragment-specific summary data without graphics instead. (Will be fixed soon.)

Showing 1 to 25 of 133 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.
pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
FRMPD4 Q14CM0 67-160 — — 4.39 N/D 0.29 0 1 / 1
LAP2 Q96RT1 1314-1412 — — 4.26 N/D 0.24 0 1 / 1
PICK1 Q9NRD5 18-110 — — 4.25 N/D 0.23 0 1 / 1
MAST2 Q6P0Q8 1102-1193 — — 4.21 N/D 0.22 0 1 / 1
TX1BP3 O14907 7-124 — — 4.19 N/D 0.21 0 1 / 1
ARHGAP21 Q5T5U3 47-159 — — 4.12 N/D 0.19 0 1 / 1
HTRA4 P83105 368-476 — — 3.98 N/D 0.14 0 1 / 1
MAST1 Q9Y2H9 965-1056 — — 3.98 N/D 0.07 0 1 / 1
LNX2 Q8N448 334-426 — — 3.96 N/D 0.14 0 1 / 1
SNX27 Q96L92 40-141 — — 3.94 N/D 0.13 0 1 / 1
SNTB1 Q13884 107-196 — — 3.92 N/D 0.11 0 1 / 1
NOS1 P29475 9-101 — — 3.90 N/D 0.11 0 1 / 1
ARHGEF11 O15085 41-126 — — 3.83 N/D 0.06 0 1 / 1
FRMPD3 Q5JV73 45-133 — — 3.78 N/D 0.1 0 1 / 1
IL16 Q14005 1203-1332 — — 3.72 N/D 0.08 0 1 / 1
IL16 Q14005 210-306 — — 3.65 N/D 0.07 0 1 / 1
TJP1 Q07157 184-264 — — 3.65 N/D 0.06 0 1 / 1
SNTA1 Q13424 84-171 — — 3.61 N/D 0.06 0 1 / 1
HTRA1 Q92743 365-480 — — 3.59 N/D 0.05 0 1 / 1
NHERF3 Q5T2W1 375-459 — — 3.59 N/D 0.06 0 1 / 1
LNX1 Q8TBB1 261-371 — — 3.58 N/D 0.04 0 1 / 1
SNTG1 Q9NSN8 54-143 — — 3.55 N/D 0.06 0 1 / 1
FRMPD2 Q68DX3 770-861 — — 3.53 N/D 0.05 0 1 / 1
DLG3 Q92796 221-314 — — 3.53 N/D 0.05 0 1 / 1
PARD3 Q8TEW0 582-685 — — 3.52 N/D 0.06 0 1 / 1
Showing 1 to 25 of 133 results
Showing 1 to 25 of 133 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.


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