Molecule type: protein
Alternative name(s): BIN1 AMPHL
External ID: O00499


Modifications

Variants

Modification: Y531S

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 513-593

This selection has only 1 possible fragment in the database.

No statistical (volcano) data available for this fragment.

Showing fragment-specific summary data without graphics instead. (Will be fixed soon.)


Showing 1 to 25 of 449 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.

pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
SRRM1 Q8IYB3 567-581 PRRRRTPTPPPRRRT 5.28 N/D 0.74 0 4 / 4
SRRM1 Q8IYB3 557-571 RRRSPSPAPPPRRRR 5.24 N/D 0.72 0 2 / 2
RSPRY1 Q96DX4 74-88 RSQPRDPVRPPRRGR 5.22 N/D 0.71 0 1 / 1
ITCH Q96J02 244-258 SNGGFKPSRPPRPSR 5.17 N/D 0.69 0 1 / 1
MRPS12 O15235 36-50 MHRLGPPKRPPRKLG 5.13 N/D 0.67 0 1 / 1
ITCH Q96J02 247-261 GFKPSRPPRPSRPPP 5.04 N/D 0.63 0 1 / 1
PDS5A Q29RF7 1259-1273 ESGPPAPSKPRRGRR 5.04 N/D 0.63 0 1 / 1
WDR44 Q5JSH3 247-261 PPPPSRPAPPPRKRK 5.03 N/D 0.62 0 1 / 1
SYNJ2 O15056 1324-1338 EAPPLVPKVPPRRKK 4.96 N/D 0.59 0 1 / 1
PRRC2C Q9Y520 1419-1433 RPRRQRPTRPPRQDK 4.88 0.06 0.55 0 5 / 5
GPATCH8 Q9UKJ3 735-749 PPGSGSPAPPRRRRR 4.86 N/D 0.53 0 1 / 1
SRRM1 Q8IYB3 365-379 SRSRSPPKKPPKRTS 4.84 N/D 0.53 0 4 / 4
PTK2B Q14289 850-864 LEFTGPPQKPPRLGA 4.83 N/D 0.52 0 1 / 1
ANKS1A Q92625 832-846 RPYEEPPQKPPRFSQ 4.78 N/D 0.49 0 1 / 1
ARAP1 Q96P48 109-123 EGLPAAPPIPPRRSC 4.71 N/D 0.46 0 1 / 1
SRRM1 Q8IYB3 544-558 GRRRRSPSPPPTRRR 4.71 N/D 0.45 0 2 / 2
SRRM1 Q8IYB3 576-590 PPRRRTPSPPPRRRS 4.70 0.37 0.45 0 5 / 5
BIRC6 Q9NR09 3927-3941 AVSATPPRPPSRRGR 4.68 N/D 0.44 0 1 / 1
ZC4H2 Q9NQZ6 209-223 KSRSRNPKKPKRKQD 4.68 N/D 0.44 0 1 / 1
YAF2 Q8IY57 3-17 DKKSPTRPKRQPKPS 4.62 N/D 0.41 0 2 / 2
SRRM2 Q9UQ35 2029-2043 RSRSRTPLLPRKRSR 4.58 N/D 0.38 0 2 / 2
WDR44 Q5JSH3 205-219 AVEEVAPAKPPRHLT 4.56 N/D 0.37 0 1 / 1
RBBP6 Q7Z6E9 725-739 RSYSRSPPYPRRGRG 4.45 N/D 0.32 0 1 / 1
PDS5A Q29RF7 1256-1270 KVDESGPPAPSKPRR 4.34 N/D 0.27 0 1 / 1
SMCHD1 A6NHR9 1977-1991 VETTDCPVPPKRMRR 4.33 0.38 0.29 0 3 / 3
Showing 1 to 25 of 449 results
Showing 1 to 25 of 449 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.



This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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