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Motif Network Search

Explore affinity networks by motif!
Search among sequence motifs using regular expressions.
Globular domains often interact with short disordered sequences showing regular chemical patterns.
  • PDZ: [ST].[ACVILF]$|[VLIFY].[ACVILF]$|[DE].[ACVILF]$ (Gogl, G. et al., Nat. Comm. 2022)
  • SH3: [RK]..P..P|P..P.[RK] (unpublished)

Motif Syntax

CharacterDescription
^Start of motif
$End of motif
.Any single residue
[...]Any residue listed
[^...]Any character except those listed
p1|p2|p3Alternation: p1 or p2 or p3
{m,n}Between m and n repetitions of previous element

Motif Examples

MotifDescription
[ST]PMotifs containing SP or TP
SP|TPMotifs SP or TP
RRE[ST].L$C-terminal motifs with S/T at the antepenultimate position
T{2,5}V$Motifs ending with V preceded by 2 to 5 T
....Motifs at least 4 residues long

Note: Searching for explicit PTMs is not available.
Motifs are centered on consensus. Some C-terminal motifs continue with "_".