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Complexome Partitioner

Numerical simulation for competitive binding systems

Calculate complexomes for competitive binding scenarios (1 receptor vs multiple ligands)

  • Analytical solutions for complex systems can be difficult (quadratic for 2 partners, cubic for 3, etc.)
  • This tool provides numerical estimation for competitive binding situations
  • Multiple ligands compete for a single receptor binding site
  • All concentrations and Kd values must have the same units (e.g. nM or µM)
  • Uses false kinetic simulation with small on-rate over many steps
  • Simple bimolecular binding mechanism assumed for all interactions
Format: Name [TAB] Concentration [TAB] Kd (one ligand per line)
More steps = higher precision, longer calculation time
Units: µM⁻¹s⁻¹