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Complexome Partitioner
Numerical simulation for competitive binding systems
Calculate complexomes for competitive binding scenarios (1 receptor vs multiple ligands)
Analytical solutions for complex systems can be difficult (quadratic for 2 partners, cubic for 3, etc.)
This tool provides numerical estimation for competitive binding situations
Multiple ligands compete for a single receptor binding site
All concentrations and Kd values must have the same units (e.g. nM or µM)
Uses false kinetic simulation with small on-rate over many steps
Simple bimolecular binding mechanism assumed for all interactions
Ligand Data (Tab-separated: Name, Concentration, Kd):
Format: Name [TAB] Concentration [TAB] Kd (one ligand per line)
Total Receptor Concentration:
Number of Steps (optional):
More steps = higher precision, longer calculation time
Arbitrary On-Rate (optional):
Units: µM⁻¹s⁻¹
Calculate Complexome