BIN1

Molecule type: protein
Alternative name(s): BIN1 AMPHL
External ID: O00499


Modifications

Variants

Modification: T532M

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 513-593

A specific fragment is selected.

See all possible fragments

No statistical (volcano) data available for this fragment.

Showing fragment-specific summary data without graphics instead. (Will be fixed soon.)

Showing 1 to 25 of 449 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.
pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
SRRM1 Q8IYB3 557-571 — RRRSPSPAPPPRRRR 5.76 0.03 0.89 0 6 / 6
SRRM1 Q8IYB3 567-581 — PRRRRTPTPPPRRRT 5.75 0.01 0.89 0 12 / 12
SYNJ2 O15056 1324-1338 — EAPPLVPKVPPRRKK 5.64 N/D 0.86 0 1 / 1
WDR44 Q5JSH3 247-261 — PPPPSRPAPPPRKRK 5.62 N/D 0.86 0 1 / 1
GPATCH8 Q9UKJ3 735-749 — PPGSGSPAPPRRRRR 5.55 N/D 0.84 0 1 / 1
SRRM1 Q8IYB3 576-590 — PPRRRTPSPPPRRRS 5.51 0.33 0.8 0 13 / 13
ARAP1 Q96P48 109-123 — EGLPAAPPIPPRRSC 5.44 N/D 0.8 0 1 / 1
RSPRY1 Q96DX4 74-88 — RSQPRDPVRPPRRGR 5.43 N/D 0.8 0 1 / 1
ITCH Q96J02 244-258 — SNGGFKPSRPPRPSR 5.41 N/D 0.79 0 1 / 1
BIRC6 Q9NR09 3927-3941 — AVSATPPRPPSRRGR 5.41 N/D 0.79 0 1 / 1
SMCHD1 A6NHR9 1977-1991 — VETTDCPVPPKRMRR 5.34 0.34 0.75 0 7 / 7
MRPS12 O15235 36-50 — MHRLGPPKRPPRKLG 5.29 N/D 0.74 0 1 / 1
CDC27 P30260 396-410 — LKMKFPPKIPNRKTK 5.26 0.09 0.73 0 13 / 13
ITCH Q96J02 247-261 — GFKPSRPPRPSRPPP 5.24 N/D 0.73 0 1 / 1
SRRM1 Q8IYB3 544-558 — GRRRRSPSPPPTRRR 5.24 0.03 0.72 0 6 / 6
SYNJ1 O43426 1278-1292 — PNLETPPQPPPRSRS 5.23 N/D 0.72 0 1 / 1
RNPS1 Q15287 237-251 — AVLAPWPRPPPRRFS 5.22 N/D 0.72 0 1 / 1
TBC1D10B Q4KMP7 15-29 — HGAPAAPSPPPRGSR 5.19 N/D 0.7 0 1 / 1
ARAP1 Q96P48 110-124 — GLPAAPPIPPRRSCL 5.13 N/D 0.68 0 1 / 1
PRR12 Q9ULL5 1664-1678 — RKPWHRPPVPVRRSG 5.13 N/D 0.67 0 1 / 1
PRRC2C Q9Y520 1419-1433 — RPRRQRPTRPPRQDK 5.11 0.08 0.66 0 13 / 13
ABL2 P42684 657-671 — MKKRNAPTPPKRSSS 5.06 N/D 0.64 0 2 / 2
DDX42 Q86XP3 920-934 — ADGFAVPEPPKRKKS 5.03 0.08 0.62 0 6 / 6
SRRM2 Q9UQ35 2029-2043 — RSRSRTPLLPRKRSR 5.02 0.02 0.62 0 6 / 6
SRRM1 Q8IYB3 327-341 — TPPRRMPPPPRHRRS 5.00 0.08 0.61 0 6 / 6
Showing 1 to 25 of 449 results
Showing 1 to 25 of 449 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.


This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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