Molecule type: protein
Alternative name(s): BIN1 AMPHL
External ID: O00499


Modifications

Variants

Modification: R581C

A specific modification is selected.

See all possible variants
Fragments

Fragments

Fragment: 513-593

This selection has only 1 possible fragment in the database.

No statistical (volcano) data available for this fragment.

Showing fragment-specific summary data without graphics instead. (Will be fixed soon.)


Showing 1 to 25 of 449 results
Name Molecule ID Fragment Modification Sequence mean pKd
Average affinity (mean of detectable pKd values)
between these molecules.

pKd = -log10Kd
Zeros (not detectable) are excluded from the mean.
std pKd
Standard deviation of pKd values
Shows the variability in measurements
Average BI
Average BI value
Considering all measurments
-log10P
If more measurements were done, the P values were combined as Pmax^K

Note that this approach is
overly conservative and
penalizing the overall result
if even one test is not
significant in order to
minimize the chance of false positives.
BDR
Binding Detection Ratio
Measured/Total
SRRM1 Q8IYB3 567-581 PRRRRTPTPPPRRRT 5.71 0.27 0.8 0 8 / 8
SRRM1 Q8IYB3 557-571 RRRSPSPAPPPRRRR 5.70 0.27 0.79 0 4 / 4
SYNJ2 O15056 1324-1338 EAPPLVPKVPPRRKK 5.62 N/D 0.75 0 1 / 1
WDR44 Q5JSH3 247-261 PPPPSRPAPPPRKRK 5.56 N/D 0.72 0 1 / 1
GPATCH8 Q9UKJ3 735-749 PPGSGSPAPPRRRRR 5.52 N/D 0.71 0 1 / 1
ARAP1 Q96P48 109-123 EGLPAAPPIPPRRSC 5.41 N/D 0.66 0 1 / 1
BIRC6 Q9NR09 3927-3941 AVSATPPRPPSRRGR 5.37 N/D 0.64 0 1 / 1
SRRM1 Q8IYB3 576-590 PPRRRTPSPPPRRRS 5.35 0.43 0.63 0 9 / 9
RSPRY1 Q96DX4 74-88 RSQPRDPVRPPRRGR 5.34 N/D 0.62 0 1 / 1
ITCH Q96J02 244-258 SNGGFKPSRPPRPSR 5.32 N/D 0.61 0 1 / 1
MRPS12 O15235 36-50 MHRLGPPKRPPRKLG 5.21 N/D 0.56 0 1 / 1
ITCH Q96J02 247-261 GFKPSRPPRPSRPPP 5.20 N/D 0.56 0 1 / 1
SMCHD1 A6NHR9 1977-1991 VETTDCPVPPKRMRR 5.19 0.40 0.56 0 5 / 5
RNPS1 Q15287 237-251 AVLAPWPRPPPRRFS 5.17 N/D 0.54 0 1 / 1
CDC27 P30260 396-410 LKMKFPPKIPNRKTK 5.16 0.19 0.55 0 9 / 9
SYNJ1 O43426 1278-1292 PNLETPPQPPPRSRS 5.16 N/D 0.54 0 1 / 1
SRRM1 Q8IYB3 544-558 GRRRRSPSPPPTRRR 5.15 0.22 0.55 0 4 / 4
PRR12 Q9ULL5 1664-1678 RKPWHRPPVPVRRSG 5.09 N/D 0.5 0 1 / 1
TBC1D10B Q4KMP7 15-29 HGAPAAPSPPPRGSR 5.08 N/D 0.5 0 1 / 1
ARAP1 Q96P48 110-124 GLPAAPPIPPRRSCL 5.07 N/D 0.49 0 1 / 1
ABL2 P42684 657-671 MKKRNAPTPPKRSSS 4.98 N/D 0.44 0 2 / 2
PRRC2C Q9Y520 1419-1433 RPRRQRPTRPPRQDK 4.96 0.20 0.45 0 9 / 9
CASKIN2 Q8WXE0 862-876 RARRKGPPPPPPKRL 4.91 N/D 0.41 0 1 / 1
SRRM2 Q9UQ35 2029-2043 RSRSRTPLLPRKRSR 4.90 0.26 0.41 0 4 / 4
RAVER1 Q8IY67 420-434 AGGGLPPELPPRRGK 4.83 N/D 0.37 0 1 / 1
Showing 1 to 25 of 449 results
Showing 1 to 25 of 449 results

You see a fragment-specific affinity binding profile, where the average affinity is shown based on all measurements done between the same fragments of the same molecules.



This selected protein appears to bind to annotated motifs!
You can use glogo to visualize its the motif preference.

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